According to the computers over at TeamRankings.com, the favorite to win it all is Indiana (21% chance).
The most likely ACC to win it all - Duke (7% chance). Future ACC member Louisville is slightly more likely to win the championship (11% chance).
Odds of an all-ACC Final Four this year? Only 0.008%. Odds if we include future members jumps up to 0.3% (still not very likely).